
Upstream Vision
What Health Should Be
Intelligent. Connected. Sustainable. Human.
A coordinated health architecture built to transform trials, care, and access — together.
Why We Are Here
Healthcare is still fragmented, inefficient, and inequitable.
Data is siloed. Trials are disconnected from care. Patients navigate alone. Foundations and NPOs have trust but lack the necessary tools. The result? A system that misses patients, loses time, and leaks value.
"Health doesn't need another app. It needs a new architecture."
The Upstream Vision
One Vision. Four Engines. Designed to Work Together — or Stand Alone.
Upstream Vision is the operating system for intelligent healthcare—a coordinated portfolio of infrastructure built to connect clinical data, AI, and biomarker analysis. Our modular platform transforms care by surfacing high-impact insights and enabling precision execution across research, delivery, and engagement—from hospital to home.
AURA
AI-driven registry and analytics platform.
Identify patients for advanced therapies, streamline coordination, and surface missed care and revenue opportunities.
iCRO
AI-native Imaging Core Lab.
Enable scalable image analysis using enterprise-grade tools designed for speed, accuracy, and real-world utility.
USHI
Patient access and engagement layer.
Help patients find trials, support, and community through trusted digital experiences.
Clinical Trials
Next-generation clinical trials infrastructure.
Accelerate enrollment and enhance data quality with a platform that unifies patient matching, imaging, and decentralized coordination.
Upstream Health Foundation
Our 501(c)(3) nonprofit arm.
Mobilizing philanthropy to ensure modern tools reach people living with serious conditions — and navigating a disconnected system.
Who We Work With
Built to Empower Stakeholders Across the Health Spectrum
✚
Hospitals & Health Systems
⚕
Trial Sponsors & CROs
⚯
Patient Foundations & NPOs
⚖
Public Sector & Advocacy
⬈
Strategic Funders & Angels
Making an Impact
15M+
patient records in AURA
25+
studies powered by iCRO
3
USHI projects deployed
3+
specialty clinical domains

Rebuilding Health from Within
Upstream Vision isn't another app or marketplace. It's a coordinated architecture of platforms and partnerships designed to transform how health systems, trials, and patients connect.
Intelligent
Connected
Sustainable
Human

Ready to Transform Healthcare Together?
Join us in building a more intelligent, connected, and human-centered health ecosystem.